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Active Research Grants

Coordinator: Alessandra Renieri

Source: HEDIMED
Title: Human exposomic determinants of immune mediated diseases
Date and cost of project: COST for our UNIT 75,000EUR
PI: Elena Bargagli

Source: MIUR, EU joint programme  - Neurodegenerative Disease Research
Title: Humanized high-throughput co-culture system for motor neuron diseases
Date and cost of project: 2020, 1.079,915EUR (149,450EUR to Silvo Conticello Unit)
PI: Eran Perlson (Tel Aviv University)

Source: AtomWise Academic  Awards
Title: Identification of APOBEC inhibitors
Date and cost of project: 2020, 5,000EUR
PI: Silvo Conticello

Source: Telethon
Title: Costruzione di una biobanca per lo studio delle malattie genetiche 
Date and cost of project:   30,000EUR
PI Alessandra Renieri

Source: Istituto Toscano Tumori (ITT)
Title: Identification of genetic bases of individual predisposition to lung cancer in non-smokers 
Date and cost of project: 118,000EUR
PI Alessandra Renieri

Source: Associazione Italiana Ricerca Cancro (AIRC)
Title: Metabolic characterization and targeting of Chronic Myeloid Leukaemia stem cells resistant to tyrosine kinase inhibitors 
Date and cost of project:       280,000EUR
PI Alessandra Renieri

Source: Comunità europea (H2020)
Title: Diagnosis and Management Of febrile illness using RNA Personalised Medicine Signature Diagnosis
Date and cost of project: 2020-2025, 400,000EUR
PI Rolando Cimaz

Source: HORIZON 2020 Comunità Economica Europea
Title: Studio dei marcatori di asma branchiale nell’adulto con approccio combinato (studio esosomi e proteomica degli esosomi)
Date and cost of project: 2020-2025
PI Elena Bargagli

Source: Regione Toscana
Title: Development of personalized diagnosis and innovative therapies for resistant CLL Development of personalized diagnosis and innovative therapies for resistant CLL
Date and cost of project:  2020-2023 euro 790,000EUR
PI: Maria De Angioletti
Capo fila progetto: Cosima Baldari

Source: Associazione Italiana per la Ricerca sul Cancro (AIRC)
Title:Metabolic characterization and targeting of Chronic Myeloid Leukaemia stem cells resistant to tyrosine kinase inhibitors 
Date and cost of project:  2020-2024, 415,000EUR/5years 
PI: Persio Dello Sbarba

Souce: Regione Toscana- Programma per la Ricerca in Materia di Salute 2018
Title: The achievable cure in Chronic Myeloid Leukemia: unravelling CD26+ leukemia stem cell features to enable safe tyrosine kinase inhibitor discontinuation - stemCMLcure
Date and cost of project: 2020-2022, 80,000EUR
Responsabile scientifico generale del progetto: prof. Monica Bocchia
PI Persio Dello Sbarba

Source: Associazione Italiana per la Ricerca sul Cancro (AIRC), IG grant
Title: Role of Hedgehog signaling in melanoma immune response
Data and cost of project: 2020-2024, 430,100EUR
PI: Barbara Stecca

Source: Bando Salute 2018
Title: Pre-clinical development and characterization of GLI-selective therapeutics for treatment of basal cell carcinoma and melanoma
Data and cost of project: 2020-2022, 400,000EUR
PI: Barbara Stecca

Source: Breast Cancer Research Foundation (BCRF), New York - USA
Title: The TOUCH trial - To reduce the use of chemotherapy in patients with ER positive and HER2 positive breast cancer
Date and cost of project:  01/10/2019-30/09/2020, 250,000USD
PI: Angelo Di Leo

Source: Associazione Italiana per la Ricerca sul Cancro (AIRC)
Title: Dissecting the role of extracellular signal-regulated kinase 5 in cellular senescence and drug resistance in melanoma
Date and cost of project: 2019-2024, 446,000 Euro
PI: Elisabetta Rovida

Source: Ente cassa risparmio Firenze
Title: Sequenziamento a nanopori di terza generazione – Oxford Nanopore per la Diagnosi Prenatale
Date and cost of project: 2019‐2020, 20,000EUR 
PI: Alessandro Maria Vannucchi, Bartalucci

Source: Regione Toscana
Title: Proton pump inhibitoRs in an elderly pOpulation and increaseD torsadES de pointTes risk (PRODEST)”
Date and cost of project: 2019-2021, 155,000EUR
PI: Pier Leopoldo Capecchi

Source: Ministero della Salute-Finalizzata
Title: CALR: Exploiting Calreticulin mutations a model for personalized medicine in MPN
Date and cost of project: 2019‐2022, 494,700EUR 
PI: Alessandro Maria Vaannucchi

Source: Ministero della salute-Finalizzata
Title: MASTO: Strategie di medicina personalizzata nella mastocitosi sistemica
Date and cost of project: 2019‐2022, 330,000EUR 
PI: Alessandro Maria Vannucchi, Paola Guglielmelli, Pieri

Source: Ministero della salute-PRIN 2017
Title: Myeloid Neoplasms: an integrated clinical, molecular and therapeutic approach
Date and cost of project: 29/08/2019‐29/08/2022 221,953EUR 
PI: Alessandro Maria Vannucchi

Source: Heidelberg university
Title: e‐MPN: European Myeloproliferative Neoplasm Network
Date and cost of project: 2019‐2023, 100,000EUR
PI: Subcontractor- Alessandro Maria Vannucchi

Source: SevenBridges Genomics
Title: Analysis of Retroelement insertions in cancer genomes
Date and cost of project: 7/2019, €10000
PI: Silvo Conticello

Source: Regione Toscana Bando Ricerca Salute 2018
Title: The achievable cure in Chronic Myeloid Leukemia: unravelling CD26+ leukemia stem cell features to enable safe tyrosine kinase inhibitor discontinuation (stemCMLcure) 
Date and cost of project: 2018-2021, 280,000EUR
PI Alessandra Renieri

Source: Associazione italiana per la ricerca sul cancro (AIRC )
Title: MYNERVA: Actionable targets in clonal progression and systemic spreading of myeloid neoplasms
Date and cost of project: 01/07/2018‐30/06/2025 2.100,000EUR
PI: Alessandro Maria Vannucchi

Source: Associazione italiana per la ricerca sul cancro (AIRC )
Title: ACCELERATOR: Early detection and intervention: Understanding the mechanisms of transformation and resistance of incurable haematological malignancies
Date and cost of project: 01/12/2018‐30/11/2023 70,000EUR/year 
PI: Alessandro Maria Vannucchi

Source: ITT GRANT 2013
Title: Mutations of calreticulin in Philadelphia‐chromosome negative chronic myeloproliferative neoplasms:understanding mechanisms and clinical correlates”
Date and cost of project: 2017‐2020 192,000EUR 
PI: Alessandro Maria Vannucchi

Source:Miur PRIN 2017-2020
Title: Flogosi sistemica e rischio aritmico: ruolo della Interleuchina-6 nel rimodellamento elettrico atriale reversibile attraverso variazioni nella espressione delle Connessine
Date and cost of project: 2017-2020, 100,182EUR
PI: Pier Leopoldo Capecchi 

Source: Italian Ministry of Health
Title:  The oncogenic potential of the AID/APOBECs: involvement in tissue transformation and oncogenesis - new tools to better model cancer   
Date and cost of project: 7/2016, €382,008
PI: Silvo Conticello