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Expired Research Grants

Source: Ministero della Salute                                                                                                
Title: “Identification of common biological pathways in Rett patients mutated in MECP2, CDKL5 and FOXG1”
Date and cost of entire project: 2012-2016          Euro 248.440,00

PI: Alessandra Renieri

Source: Telethon                                                                                               
Title: “Cell lines and DNA bank of Rett syndrome, X-linked mental retardation and other genetic diseases”
inside the general project: "Telethon Network of Genetic Biobanks"
Date and cost of entire project: 2013-2017         Euro 37.000,00 per year

PI: Alessandra Renieri

 

Source: Associazione Italiana per la ricerca sul Cancro

Title: "Melanoma cell therapy: endothelial progenitor cells as shuttles of anticancer agents"

Date and cost of entire project: 2013-2016        Euro 255.000

PI: Mario Del Rosso

 

Source: Italian Cystic Fibrosis Research Foundation

Title: "GSH inhalation therapies in CF : how useful, how safe? Set-up of a CF murine model for monitoring of inflammation in vivo and assessment of convenient alternatives"

Date and cost of entire project: 2014-2016         Euro 56000

PI: Alessandro Corti


Source: Ministero della Salute

Title: "The oncogenic potential of the AID/APOBECs: involvement in tissue transformation and oncogenesis - new tools to better model cancer"

Date and cost of entire project: 2014-2017        Euro 341.387,16 (Euro 183.228,14 for the PI)

PI: Laura Poliseno

 

Source: Provincia Autonoma di Trento

Title: "Studio clinico e genetico di pazienti con malformazioni vascolari ad eredità mendeliane - 2. Clonaggio e studio funzionale di nuove mutazioni di FOXC2 - 3. dentificazione di nuovi geni-malattia attraverso l'intero esoma di famiglie con malformazioni vascolari ad eredità mendeliane - 4. Studio di mutazioni somatiche in campioni bioptici di malformazioni vascolari ad eredità mendeliane"

Date and cost of entire project: 2015-2016        Euro 700.000

PI: Matteo Bertelli

 

Source: University of Pisa

Title: "Nuovi fattori patogenetici e marker diagnostici di progressione dell’Artrite reumatoide"

Date and cost of entire project: 2015-2016              Euro 35.000

PI: Alfonso Pompella

 

Source: Istituto Toscano Tumorit

Title: "Peripheral arterial occlusive disease in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: role for a drug induced pro-atherothrombotic status"

Date and cost of entire project: 2015-2017        Euro 93.000

PI: Monica Bocchia

 

Source: Associazione Italiana per la Riceca sul Cancro

Title: "Prospective study of tyrosine kinase inhibitors induced pro-atherothrombotic status in chronic myeloid leukemia patients"

Date and cost of entire project: 2015-2017        Euro 153.000

PI: Monica Bocchia

 

Source: Istituto Toscano Tumori

Title: "Role of ERK5 in the selection of Chronic Myeloid Leukaemia cells in hypoxia in the design of strategies to suppress Minimal Residual Disease"

Date and cost of entire project: 2015-2018        Euro 209.000

PI: Persio Dello Sbarba

 

Source: Istituto Toscano Tumori

Title: "Acidity in tumor environment: Molecular bases to interfere with malignant progression and cancer stem cells"

Date and cost of entire project: 2015-2018        Euro 172.000

PI: Lido Calorini

 

Source: Novartis

Title: "preclinical study for optimizing cml stem cells detection by flow-cytometry"

Date and cost of entire project: 2016                  Euro 22.000

PI: Monica Bocchia

 

Source: ECRF

Title: "Valutazione preclinica di nuovi antagonisti RGD e di inibitori delle metalloproteasi ad attività gelatinasica mediante analisi microPET/SPECT/CT"

Date and cost of entire project: 2016-2017        Euro 25.000

PI: Lido Calorini


Source: Regione Toscana, Bando Istituto Toscano Tumori

Title: "Mutations of calreticulin in myeloproliferative neopalsms: understanding mechanisms and clinical correlated"

Date and cost of entire project: 2016-2019        Euro 190.000

PI: Alessandro Maria Vannucchi


Source: Associazione Italiana per la ricerca sul Cancro, 5 per Mille

Title: "An integrated platform for clinical and molecular studies in myeloproliferative neoplasms"

Date and cost of entire project: 2016-2017        Euro 1.000.000

PI: Alessandro Maria Vannucchi

 

Source: Associazione Italiana per la ricerca sul Cancro

Title: "APOBEC1 in cancer development: a dual path to cancer"

Date and cost of entire project: 2016-2018        Euro 320.000

PI: Silvestro Conticello


Source: Associazione Italiana per la ricerca sul Cancro

Title: "miR-204 inhibition and attenuated Listeria monocytogenes: development of a novel therapeutic strategy against melanoma"

Date and cost of entire project: 2016-2018        Euro 221.000

PI: Laura Poliseno


Source: Ministero della Salute

Title: "The oncogenic potential of the AID/APOBECs: involvement in tissue transformation and oncogenesis - new tools to better model cancer"

Date and cost of entire project: 2016-2019        Euro 382.008 (Euro 305.619 for the PI)

PI: Silvestro Conticello

Source: Milheim Foundation For Cancer Research

Title: "The Adenovirus E1A Transforming region associate in vitro with two novel cellular factors"

Date and cost of entire project: 1993-1994           $ 15,000

PI: Antonio Giordano

 

Source: W. W. Smith Charitable Trust

Title: "Characterization and Identification of Novel Tumor Suppressor Genes"

Date and cost of entire project: 1993-1995           $ 184,000

PI: Antonio Giordano


Source: Telethon
Title: "Molecular Genetics of Alport syndrome"
Date and cost of entire project: 1994-1996          Lire 85.000.000
PI: Alessandra Renieri

 

Source: NIH RO1

Title:  "p130/Rb2 a Novel Target for the Ad5 E1A Oncoproteins"

Date and cost of entire project: 19941997             $ 447,000

PI: Antonio Giordano

 

Source: The Council for Tobacco Research

Title: "The Role of pRb2 in Cell Proliferation"

Date and cost of entire project: 1995-1998            $ 150,000

PI: Antonio Giordano

 

Source: Sbarro Institute for Cancer research and Molecular Medicine

Title: "Cancer and Cell Cycle"

Date and cost of entire project: 1995-1999            $ 600,000

PI: Antonio Giordano

 

Source: Istituto Farmacoterapico Italiano (IFI)

Title: "Molecular cloning of the Tumor Liberated Protein (TLP)"

Date and cost of entire project: 1996-1997            $ 64,000

PI: Antonio Giordano


Source: Telethon
Title: "Cloning and characterization of the genes responsible for a new X-linked contiguous gene syndrome including Alport phenotype, mental retardation and elliptocytosis"
Date and cost of entire project: 1996-1998            Lire 148.000.000
PI: Alessandra Renieri

 

Source:  The Council for Tobacco Research

Title: "The Role of pRb2 in Cell Proliferation"

Date and cost of entire project: 1998-1999            $ 35,000

PI: Antonio Giordano


Source: Associazione Emma ed Ernesto Rulfo per la Genetica Medica
Title: "Progressi verso la identificazione della base genetica della sindrome di Rett"
Date and cost of entire project: 1999-2001           Lire 30.000.000; anno 2003 Euro 13.000.
PI: Alessandra Renieri


Source: MURST cofin
Title: "Corrispondenza tra genotipo e fenotipo nell'eredità del glaucoma primario ad angolo aperto".
Date and cost of entire project: 1999-2001           Lire 154.000.000
PI: Alessandra Renieri


Source: Telethon
Title: "Molecular basis of AMME contiguous gene syndrome (A=Alport phenotype, M=mental retardation, M=midface hypoplasia and E=elliptocytosis) and single gene / phenotype correlation"
Date and cost of entire project: 2000-2003          Lire 306.000.000
PI: Alessandra Renieri

 

Source: PAR Università di Siena
Title: "Uso delle sequenze della Celera Genomics nell'era post-genomica e esempio di applicazione alle malattie neuropsichiatriche: Autismo e Complesso della Sindrome di Rett"
Date and cost of entire project: 2001                   Lire 35.000.000
PI: Alessandra Renieri


Source: SOI
Premio ricerca scientifica SOI 2002
Date and cost of entire project: 2002                   Euro 20.000,00
PI: Alessandra Renieri

 

Source: National Cancer Institute  NIH R21 CA94802-01

Title: "Functional Interaction between HIV-1 products and cell cycle proteins"

Date and cost of entire project: 2002-2004          $ 100,000    20% effort

PI: Antonio Giordano


Source: PAR Università di Siena
Title: "Ruolo dei geni FACL4 e LAMA2 nella patogenesi della Sindrome di Rett e di disordini correlati"
Date and cost of entire project: 2002                   Euro 24.000,00
PI: Alessandra Renieri

 

Source: NIH RO1 CA094804-02          

Title: "Human Neurotropic JC Virus and CNS Diseases"

Date and cost of entire project: 2002-2006         $ 222,500
P.I.: K. Khalili Co P.I.: A. Giordano, 10% effort

 

Source: PA Dept of Health

Title: “Cancer Biomolecular Markers Research “                       

Date and cost of entire project: 2007- 2009        $ 2,000,000

PI: Antonio Giordano

 

Source: Ministero della Salute

Title: “Genomic structural variation studies in mentally retarded and normal individuals in Italy”.

Date and cost of entire project: 2008- 2010       Euro 90.200,00

PI: Alessandra Renieri

 

Source: PA Dept of Labor & Industry: 

Title: “Workforce Development Grant”                         

Date and cost of entire project: 2009                 $ 200,000   

PI: Antonio Giordano

 

Source: Commonwealth of PA  

Title: “Redevelopment Assistance Capital Project”              

Date and cost of entire project: 2009                $ 1,500,000 

PI: Antonio Giordano

 

Source: Department of Defense

Title: “Cancer Biomolecular Markers Research”                  

Date and cost of entire project: 2009-2010       $ 1,000,000    

PI: Antonio Giordano

 

Source: A.I.R. (Associazione Italiana Rett)

Title: “Produzione di cellule neuronali da fibroblasti riprogrammati di pazienti con Sindrome di Rett: una tecnologia innovative per testare strategie terapeutiche”.

Date and cost of entire project: 2009-2010       Euro 50.000,00

PI: Alessandra Renieri

 

Source: PA Dept of Health 

Title: “Identification of Cancer Stem Cells – a Powerful Weapon to Fight Cancer”                             

Date and cost of entire project: 2009-2010       $ 500,000

PI: Antonio Giordano

 

Source: PA Dept of Health:

Title: “Cancer Biomolecular Markers Research “                       

Date and cost of entire project: 2009- 2010     $ 2,000,000

PI: Antonio Giordano

 

Source: PA Dept of Labor and Industry: 

Title: "Workforce Development Grant-Training Program”

Date and cost of entire project: 2010               $ 300,000 

PI: Antonio Giordano

 

Source: PA Dept of Community and Economic Development

Title: “Lung Cancer Biotechnology Research and Training Project

 Date and cost of entire project: 2008-2012          $ 1.4M

PI: Antonio Giordano

 
Source: Comune di Milano
Title: "Prolife: danni alla salute da inquinamento ambientale"
Date and cost of entire project: 2007-2010           Euro 300.000,00
PI: Francesco Cetta
 

Source: Ministero della Salute                                                                                               

Title: “Classificazione clinico-molecolare di pazienti con sindrome di Rett e ruolo di leptina e adiponectina nel fenotipo somatico”

Date and cost of entire project: 2010-2012           Euro 34.900,00

PI: Francesca Mari

 

Source: Commonwealth of PA  

Title: “Redevelopment Assistance Capital Project”              

Date and cost of entire project: 2010-2012            $ 3,000.000    

(Included in State budget-pending formal award)

PI: Antonio Giordano

 

Source: IRSF (International Rett syndrome Foundation)                                                    

Title: “International Rett syndrome database”

Date and cost of entire project: 2010-2011          $ 5.000,00”

PI: Alessandra Renieri

 

Source: Regione Toscana                                                                                                         

Title: “Percorso diagnostico-assistenziale per pazienti affetti dalla sindrome di Rett”

Date and cost of entire project: 2010-2011         Euro 10.000,00

 PI: Alessandra Renieri

 

Source: Regione Toscana                                                                                                         

Title: “Percorso diagnostico-terapeutico per pazienti affetti da Sindrome di Alport e nefropatie correlate”

Date and cost of entire project: 2010-2011        Euro 10.000,00

PI: Alessandra Renieri

 

Source: Regione Toscana                                                                                                        

Title: “Ottimizzazione del percorso diagnostico-assistenziale per pazienti affetti da malattie genetiche rare”

Date and cost of entire project: 2010-2011        Euro 10.000,00

PI: Alessandra Renieri

 

Source: Telethon
Title: “Congenital Rett syndrome: cellular and mouse models for the study of FOXG1 impact on forebrain neurogenesis.”
Date and cost of entire project: 2009- 2014         Euro 293.100,00
PI: Alessandra Renieri

 

Source: Ministero della Salute                                                                                                
Title: “Induced pluripotent stem cells as in vitro models for the study of Rett syndrome pathogenesis and identification of therapeutic targets”
Date and cost of entire project: 2011-2014          Euro 164.120,00

PI: Alessandra Renieri


Source: AIRETT

Title: "Analisi dei geni HLA per individuare la suscettibilità genetica ai vaccini come componente della sindrome di Rett"

Date and cost of entire project: 2012-2014     Euro 25.000,00


Suorce: Telethon

Title: "Molecular bases and in vitro modeling of CDKL5 dependent infantile neurological disorders"

Date and cost of entire project: 2011-2014     Euro 108.400,00