Home‎ > ‎Research‎ > ‎Research Projects‎ > ‎

Patents Awarded

Renieri A, Conticello S, Pinto AM, Meloni I, Daga S, Donati F, Croci S, Lopergolo D. “CRISPR-Cas system for gene therapy” (Patent application N° 102018000020230) for the use of CRISPR/Cas9 technology in rare genetic diseases. December 19, 2018. 

Renieri A, Conticello S, Donati F, Niccheri F, Mari F, Papa FT, Lorenzetti FC. “Sistema CRISPR-Cas per l’editing genomico” (Patent application N° 102018000009431) for the employment of CRISPR/Cpf1 technology for specific delivery of suicide gene in cancer cells mutated in TP53. October 15, 2018.

Antonio Giordano, “Peptide inhibitors of cyclin-dependent kinase activity and uses thereof” U.S. Patent No. 7,470,670

 

Antonio Giordano “Human cyclin-dependent kinase-like proteins and methods of using the same.” U.S. Patent No. 6,822,080 Issued: 11/23/2004


Alessandra Renieri e Ilaria Meloni "Diagnostic and therapeutic tools for X-linked mental retardation syndrome " International application No PCT/IT03/00134) issued March 2003 (se also research activity on Mental Retardation)

 

Antonio Giordano “A Method of Inhibiting Cancer Cell Growth Using a Vector Expressing pRb2/P130.” U.S. Patent No. 6,663,856 Issued:  12/16/2003

 

Antonio Giordano “Methods of Inhibiting Smooth Muscle Cell Proliferation and Preventing Restenosis with a Vector Expressing Rb2/P130.” U.S. Patent No. 6,596,698 Issued:  07/22/2003

 

Antonio Giordano  "pRb2/p130 Peptide Inhibitors of cdk2 Kinase activity" U.S. Patent No. 6,297,357 issued on October 2 2001.

 

Antonio Giordano "Determination of Cyclin-Dependent Kinase Inhibitor p27 levels as a prognostic factor in cancer patients." U.S. Patent No. 6,180,333 issued on January 30, 2001.

 

Antonio Giordano, “Human Cyclin-Dependent Kinase-like Proteins and Methods of Using the Same,” U.S. Patent No. 6,162,612, issued on December 19, 2000.

 

Antonio Giordano and A. Baldi, “Human Retinoblastoma-Related (pRb2/p130) Genomic DNA and Methods of Detecting Mutations Therein. US. Patent Patent No. 5,807,681, issued on Sep. 15, 1998.

 

Antonio Giordano, “Human Cyclin-Dependent Kinase-like Proteins and Methods of Using the Same,” U.S. Patent No. 5,674,748, issued on October 7, 1997.

 

Antonio Giordano, ”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” U.S. Patent No. 5,532,340, issued July 2, 1996.

 

Antonio Giordano, ”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” U.S. Patent No. 5,457,049, issued October 10, 1995.