The University of Siena PhD Course in
Genetics, Oncology and Clinical Medicine


PhD Graduate

Valentina GUERCIO 

PhD Program years: 2009 - 2013







PUBLICATIONS DURING THE PHD PROGRAM
    1. Epidemiology, public health, and false-positive results: the role of the clinicians and pathologists.
    Cetta F, Benoni S, Zangari R, Guercio V, Monti M.
    Environ Health Perspect. 2010 Jun;118(6):A240.
ABSTRACTS OF CONFERENCE DURING THE PHD PROGRAM

1) Variabilità stagionale del PM e degli outcomes clinicamente rilevanti. Correlazioni di studi in vitro e nell'uomo sulla funzione respiratoria nella città di Milano (4° Convegno Nazionale sul Particolato Atmosferico, Venezia, Italia, 18/5/2010)

2) Unpredictability of the Actual Reduction of Negative Health Effects of Air Pollution Because of Contrast Measure Reducing PM Concentration in µg/m3 (American Association of Aerosol Research,: San Diego, California, 22-26/3/2010)

3) Traffic Related Respiratory Alterations in Schoolchildren in Milan, Italy (International Aerosol Conference 2010, Helsinki, Finland 29/8/2010-3/9/2010)

4) Traffic Related Respiratory Alterations in Schoolchildren in Milan, Italy (American Association of Aerosol Research, San Diego, California USA, 22-26/3/2010.

5) The role of Air Pollution in the occurrence of Rheumatoid Arthritis: biological and pathophysiological suggestions by an in vitro study (Urban Environmental Pollution 2010, Boston, USA, 20-23/6/2010)

6) The impact of traffic pollution on antioxidant system of two populations exposed to different levels of pollutants: estimation of redox status of thiols. (International Aerosol Conference 2010, Helsinki, Finland, 29/8/2010- 3/9/2010)

7) The actual reduction of negative health effects because of contrast measures reducing PM concentration (µg/m3) is unpredictable (International Aerosol Conference 2010, Helsinki, Finland, 29/8/2010-3/9/2010)

8) The Role of "Individual Susceptibility" in Pollution Related Diseases and the Impact of PM Concentration on the Occurrence of "Acquired Susceptibility (American Association of Aerosol Research San Diego, USA, 22-26/3/2010).

9) The Role of "Individual Susceptibility" in Pollution Related Diseases and the Impact of PM Concentration on the Occurrence of "Acquired Susceptibility" (American Association of Aerosol Research San Diego, USA, 22-26/3/2010).

10) Target-oriented risk assessment for air pollution in Milan: preliminary results. (International Aerosol Conference 2010, Helsinki, Finland, 29/8/2010- 3/9/2010)

11) Role of "individual susceptibility" in pollution related diseases and the impact of PM concentration on the occurrence of "acquired susceptibility" (Urban Environmental Pollution 2010 Boston USA 2-23/6/2010)

12) Reduction Of PM Concentration Below Certain Levels Is Going To Determine Lower Than Expected Beneficial Health Outcomes On Resident Population (Urban Environmental Pollution 2010 Boston USA 2-23/6/2010)

13) Redox Balance of Thiols in the Exhaled Breath Condensate (EBC) in Addition to Blood Samples in Two Populations with Different Exposure to Traffic Related Pollutants. (American Association of Aerosol Research 2010, Sede: San Diego California, USA)

14) Oxidative Stress and Thiol Imbalance In Blood and Breath In 2 Populations With Different Exposure To Air Pollution (Urban Environmental Pollution 2010 Boston USA 2-23/6/2010)

15) Measurement of damages to exposed populations during concomitant evaluation of PM concentration and health effects usually doesn't consider damage to newborns. (International Aerosol Conference Helsinki, Finlandia, 29/8/2010-3/9/2010)

16) L'imprevedibilità dell'effettiva riduzione degli effetti dannosi dell'inquinamento atmosferico sulla salute sulla base delle misure di contrasto per ridurre la concentrazione di pm (ng/m3) (4° Convegno Nazionale sul Particolato Atmosferico, Venezia, Italia,: 18/5/2010-20/5/2010)

17) Inquinamento atmosferico e artrite reumatoide: uno studio in vitro sui sinoviociti umani fibroblasti-simili (4° Convegno Nazionale sul Particolato Atmosferico, Venezia, Italia, 18/5/2010-20/5/2010)

18) Exposure to Short Duration Peaks of Indoor PM10 is not associated with clinically evident effects in children attending Primary School: a Prospective Study. (International Aerosol Conference, Helsinki, Finland, 29/8/2010-3/9/2010)

19) Exposure of newborns to high PM concentration affects "acquired susceptibility", determining an increased prevalence of "susceptible individuals" (“International Aerosol Conference 2010, Helsinki, Finland ,29/8/2010-3/9/2010)

20) Epidemiological studies on health effects from air pollution give inconclusive results because lack of adequate metrics of exposure, effect and susceptibility Measurement of damages to exposed populations during concomitant evaluation of PM concentration and health effects usually doesn't consider damage to newborns (“International Aerosol Conference 2010, Helsinki, Finland ,29/8/2010-3/9/2010)

21) Environmental pollution in Metropolitan Areas and alterations of respiratory function in asymptomatic subjects (“International Aerosol Conference 2010, Helsinki, Finland ,29/8/2010-3/9/2010)

22) Environmental Pollution in Metropolitan Areas and COPD (Chronic Obstructive Pulmonary Diseases (American Association of Aerosol Research ,San Diego, California, USA, 22-26/3/2010)

23) Different Pulmonary Function and Predisposition To Respiratory Diseases In Metropolitan Areas and Remote Alpine Sites, Because Of Different Air Pollution (Urban Environmental Pollution 2010,BOSTON, USA, 20-23/6/2010)

24) Concomitant study by the same team of obesity prevalence, body mass index and pollution related health effects in children attending primary school in Milan, Italy (NIEHS-EPA Symposium on air Pollution and Cardiovascular Disease, Seattle,USA, 21-22/6/2010)

25) Comparison of In Vitro Results of PM Incubation with Cell-Lines with Clinical Effects in Children Exposed to the Same Particles from the Same Urban Area. The Milan Prolife Project (American Association of Aerosol Research 2010 ,San Diego, USA, 22/3/2010-26/3/2010)

26) Bilancio redox dei tioli nel Condensato dell'esalato bronchiale (EBC) e in campioni ematici di 2 popolazioni con differente esposizione agli inquinati correlati al traffico (4° Convegno Nazionale sul Particolato Atmosferico, Venezia, Italia, 18-20/5/2010)

27) An "in vitro" study supporting the possible impact of air pollution on Rheumatoid Arthritis (International Aerosol Conference , Helsinki, Finlandia, 29/8/2010-3/9/2010)

28) Alterazioni respiratorie correlate al traffico: studio prospettico nelle scuole elementari milanesi (4° Convegno Nazionale sul Particolato Atmosferico,Venezia, Italia, 18-20/5/2010)

29) Air Pollution and Rheumatoid Arthritis: an In Vitro Study on Human Fibroblast-Like Synoviocytes (American Association of Aerosol Research 2010 ,San Diego,USA, 22-26/3/2010)

30) Acute cardiovascular effects associated with air pollution: a new pathogenetic pathway in patients with chronic obstructive pulmonary diseases (COPD) also evaluated using a realistic hollow airway replica of the tracheo-bronchial tree (NIEHS-EPA Symposium on air Pollution and Cardiovascular Disease ,Seattle, USA, 21-22/6/2010)

31) Absence of Clinically Evident Effects because of Short Duration Peaks of Indoor PM10 During a Prospective Study in Children Attending Primary School. (American Association of Aerosol Research 2010,San Diego, California, 22-26/3/2010)

32) A target - oriented risk assessment for air pollution in Milan: preliminary results. (International Aerosol Conference, Helsinki, Finlandia, 29/8/2010 -3/9/2010)

33) A comparative study on the outcomes between in vitro results of PM incubation with cell-lines and clinical effects in children. The Milan Prolife Project. (International Aerosol Conference 2010,Helsinki, Finland, 29/8/2010- 3/9/2010)

34) A comparative study on the outcomes between in vitro results of PM incubation with cell-lines and clinical effects in children (International Aerosol Conference ,Helsinki,Finlandia, 29/8/2010 -3/9/2010)

35) Perinatal susceptible window” as a main responsible for cardiovascular and respiratory diseases occurring later in life because of PM exposure (EAC 2011; 4 September –9 September 2011, Manchester, England)

36) A 3-year-follow-up Study of Traffic Related Respiratory Alterations in school children in Milan, Italy (EAC 2011; 4 September –9 September 2011, Manchester, England.)

37) A plea for a more “doubtful” and “skeptic” approach to the role of intrinsic toxicity of airborn pollutants as the main responsible for observed cardiovascular, respiratory and cancerous diseases or deaths in humans. (EAC 2011; 4 September –9 September 2011, Manchester, England.)

38) Alteration of respiratory function in asymptomatic subjects living in Milan (Italy) and in Aprica (Italy), an Alpine site with different levels of environmental pollution. Spirometric and laboratory evaluation. (EAC 2011; 4 September –9 September 2011, Manchester, England.)

39) Comparison between in vitro results of PM incubation with cell-lines and health effects in children. (EAC 2011; 4 September –9 September 2011, Manchester, England.)

40) Environmental pollution in Metropolitan Areas and alterations of respiratory function. (EAC 2011; 4 September –9 September 2011, Manchester, England.)

41) Measurement of damages to exposed populations during concomitant evaluation of PM concentration and health effects usually doesn’t consider damage to newborns. European Aerosol Conference (EAC 2011) 4 September –9 September 2011, Manchester, England.

42) Mesothelioma incidence is likely not going to decline, despite asbestos ban in Western countries.European Aerosol Conference (EAC 2011) 4 September –9 September 2011, Manchester, England

43) Selection of proper markers for a better knowledge of health effects of air pollution. Difficulty in the choice of markers or in the recognition of causative mechanisms? European Aerosol Conference (EAC 2011) 4 September –9 September 2011, Manchester, England.

44) The “harmful potential” of PM, evaluated “in vitro” must be used with a great causation as a surrogate for risk assessment in humans. European Aerosol Conference (EAC 2011) 4 September –9 September 2011, Manchester, England.

45) The inflammatory response elicited in vitro by air pollutants is greater in synoviocytes from patients with Rheumatoid Arthritis than in those with osteoarthrosis European Aerosol Conference (EAC 2011) 4 September –9 September 2011, Manchester, England.

46) NEOPLASIE ASSOCIATE NEI PAZIENTI CENTENARI E ULTRACENTENARI. LA “LONGEVITY” PUÒ COESISTERE CON ALCUNI TIPI DI NEOPLASIA (SIGG; 56° Congresso Firenze, 29/11/2011 - 03/12/2011

47) OSTEOPOROSI E “FRAGILITY FRACTURES” NEI CENTENARI E NEGLI ULTRACENTENARI DEGENTI PRESSO L’ISTITUTO GERIATRICO PIO ALBERGO TRIVULZIO DI MILANO. (SIGG) 56° Congresso Firenze, 29/11/2011 - 03/12/2011

48) ELEVATA PREVALENZA DI NEOPLASIE ALTRIMENTI INFREQUENTI NEI PAZIENTI CON SINDROME DI WERNER. NON SI TRATTA DI SEMPLICE ED ASPECIFICA ANTICIPAZIONE DEL PROCESSO DI INVECCHIAMENTO
(SIGG) 56° Congresso Firenze, 29/11/2011 - 03/12/2011

49) IL TRENO VIRTUALE: INNOVATIVO PERCORSO DI CURA IN RSA ALZHEIMER (SIGG) 56° Congresso Firenze, 29/11/2011 - 03/12/2011

50) LA FASE DEGLI ESITI NELLE PERSONE IN STATO VEGETATIVO: SPERANZA DI VITA E QUALITA’ DELL’ASSISTENZA. (SIGG) 56° Congresso Firenze, 29/11/2011 - 03/12/2011

51) BISOGNI ASSISTENZIALI DI ANZIANI ULTRANOVANTENNI RILEVATI DURANTE LA DEGENZA IN HOSPICE (SIGG) 56° Congresso Firenze, 29/11/2011 - 03/12/2011.

52) CARATTERISTICHE DEMOGRAFICHE, FISIO-PATOLOGICHE, PSICO-COGNITIVE E FUNZIONALI NEI CENTENARI E ULTRACENTENARI RICOVERATI AL PIO ALBERGO TRIVULZIO NEL TRIENNIO 2008-2010 (SIGG) 56° Congresso
Firenze, 29/11/2011 - 03/12/2011

53) A deeper insight into pathophysiologic mechanisms or a prerequisite for the proper selection of markers of health effects of air pollution. VALENTINA GUERCIO, M. Monti, L. Bergamaschini, L. Moltoni, P. Laviano, F. Cetta, et al., 5C.311C. AAAR 30th Annual Conference. OctOber 3 – 7, 2011 • Orlando, Florida

54) Environmental factors (traffic pollution) facilitate the occurrence of rheumatoid arthritis in predisposed individuals. M. Galeazzi, L. Moltoni, F. Tani, S. Benoni, V. GUERCIO, F. Cetta, et al.,11C.6. AAAR 30th Annual Conference. October 3 – 7, 2011 • OrlandO, Florida

55) Damage to newborns, during the “Perinatal susceptible window” could be responsible for cardiovascular and respiratory diseases occurring later in life because of PM exposure. L. Moltoni, M. Sala, V. GUERCIO, R. Zangari, P. Laviano, F. Cetta, et al., 7C.2. AAAR 30th AnnuAl Conference. October 3 – 7, 2011 • OrlandO, Florida

56) Alteration of respiratory function in asymptomatic subjects because of environmental pollution is greater in Metropolitan Areas then in remote Alpine site. F. Cetta, G. Schiraldi, M. Monti, L. Bergamaschini, J. Martellucci, R. Zangari,V. GUERCIO et al., 5C.4. AAAR 30th Annual Conference. October 3 – 7, 2011 • OrlandO, Florida

57) Mesothelioma incidence is likely not going to decline, despite asbestos ban in Western countries. G. Gotti , F. Cetta, P. Paladini, L. Bergamaschini, V. GUERCIO et al.,7C.6. AAAR 30th Annual Conference. October 3 – 7, 2011 • Orlando, Florida

58) Traffic Related Respiratory Alterations in Schoolchildren in Milan, Italy. A 3-year-follow-up Study. M. Sala, F. Cetta, S. Argirò, M. Mandelli, L. Moltoni, E. Bolzacchini, V.GUERCIO et al. AAAR 30th Annual Conference. October 3 – 7, 2011 • Orlando, Florida.

59) Elevata prevalenza di neoplasie altrimenti infrequenti nei pazienti con sindrome di Werner. Non si tratta di semplice ed aspecifica anticipazione del processo di invecchiamento F. Cetta, M.V. Masala, A. Federico, S. Benoni, A. Puca, M. Monti, L. Moltoni, V. GUERCIO, R. Zangari1, C. Gotti. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011, (Abs pag 447)

60)La fase degli esiti nelle persone in stato vegetativo:speranza di vita e qualità dell’assistenzaP. Di Vincenzo, M. Zanetti, M. Monti, O. Caratozzolo, F. Cetta, V. GUERCIO, F. Giunco. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011 (Abs pag 466)

61) Il treno virtuale: innovativo percorso di cura in RSA Alzheimer M. Gandelli, M. Gianotto, I. Cilesi, R. Ferrari, A. Fasolino, M. Scarangella,V. GUERCIO, F. Cetta, M. Monti. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011 (Abs, pag 477)

62) Neoplasie associate nei pazienti centenarie ultracentenari: la “LONGEVITY” può coesistere con alcuni tipi di neoplasie V. GUERCIO, R. Zangari, L. Moltoni, S. Civitelli, S. Baruffi, E. La Russa, M. Gandelli, M. Gianotto, D. Moretti, F. Cetta, M. Monti. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011 (Abs, pag 489)

63) Osteoporosi e “Fragility fractures” nei centenari e negli ultracentenari degenti presso l’istituto Geriatrico Pio Albergo Trivulzio di Milano P. Laviano, F. Cetta, V. GUERCIO, R. Zangari, L. Moltoni, M. Monti, L. Bergamaschini, C.I. Zanoni, P.L. Rossi,C. Quaranta, I. Santi. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011 (Abs, pag 498)

64) Bisogni assistenziali di anziani ultranovantenni rilevati durante la degenza in hospice M. Monti, V. GUERCIO, M. Di Caprio, A. Giardullo, L. Giambarresi, R. Romani, F. Cetta, L. Castellani. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011 (Abs, pag 515)

65) Caratteristiche demografiche, fisio-patologiche, psicocognitive e funzionali nei centenari e ultracentenari ricoverati al Pio Albergo Trivulzio nel periodo 2008-2011 D. Moretti, V. GUERCIO, R. Zangari, F. Cetta, M. Gandelli, M. Gianotto, P. Di Vincenzo, E. La Russa, L. Bergamaschini, M. Monti. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011 (Abs, pag 516)

66) Demenza e patologia oncologica: analisi di una popolazione di pazienti anziani affetti da demenza ricoverati in un nucleo Alzheimer I.D.R. C. Negri Chinaglia, I. Engaddi, L. Pelucchi, G. Savorgnan, V. GUERCIO, F. Cetta. Atti, 56° Congresso SIGG Firenze, 29/11/2011 – 03/12/2011 (Abs pag 522)

67) Terapia della bambola: feedback del caregiver formale nei nuclei RSA Alzheimer. Gandelli M, Gianotto M, Cilesi I, Ferrari R, Fasolino A, Scarangella M, GUERCIO V, Cetta F,
Monti M. Psicogeriatria 1(suppl): 142 (abstr), 2011. Atti XI Congresso Nazionale Psicogeriatria. Gardone Riviera, 15-19 maggio 2011.

68) Ultracentenari: Nuona area di ricerca? F. Cetta, V. GUERCIO, M. Monti. 25° Congresso nazionale della Società Italiana di Chirurgia Geriatrica. S.I.C.G., Padova, Maggio 2012

69) Gli ultracentenari sono relativamente risparmiati dalla patologia tumorale. L’esperienza del Pio Albergo Trivulzio. F. Cetta, V. GUERCIO, G. Ugolini, M. Monti. XXIV Congresso Nazionale della Società Italiana di Chirurgia Geriatrica 10-12 Novembre 2011, Orbassano, Torino

70) Anziani, residenze sanitarie assistenziali e cure palliative Monti M, Moretti D, Cast Gianotto M, Gandelli M, Di Vincenzo P, Guercio V, Cetta F.. Rivista Italiana di Cure Palliative n3, autunno 2011.

ACTIVITY DURING THE PHD PROGRAM

TRAINING PERIOD ABROAD
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