Paola Guglielmelli 

Paola Guglielmelli graduated in Medicine in 2003 at the University of Florence and then she obtained a specialty in Hematology in 2007 at the same University. From 2015, she is a researcher scientist in Hematology at the University of Florence. In 2007 visiting scientist at INSERM U790, Institut Gustave Roussy (director Dr. William Vainchenker), Villejuif ( Paris) and in 2010 visiting scientist at the National Genetics Reference Laboratory (Wessex), Salisbury NHS Foundation Trust (Director Professor NCP Cross), Salisbury Wiltshire, UK. She is a member of CRIMM (center for research and Innovation for Myeloproliferative Neoplasms) of Azienda Ospedaliero-Universitaria Careggi and University of Florence. Her main scientific interests concern experimental and clinical issues of myeloproliferative neoplasms (MPN). She has been working on the molecular characterization of the gene expression profile in hematopoietic progenitors of patients with MPN and she has more recently completed some observations concerning epigenetic mechanisms in MPN. She has been also involved in the study of a novel animal model of myelofibrosis, the GATA-1 low and CALR mut mice. Current areas of research include preclinical studies on JAK-STAT pathway, Calreticulin and PI3K/Akt/mTOR pathways as a therapeutic target in myeloproliferative neoplasms, coding and not-coding RNA expression profile, exome and RNA sequencing. Furthermore, she is strongly committed to clinical work, having in routine charge patients with MPNs and being involved in phase I-IV clinical studies with novel drugs and in epidemiologic studies. She is the Principal Investigator of Research projects supported by official and non-profit organization, including Ministry of Health and AIRC (Associazione Italiana per la Ricerca sul Cancro). She is author of more than 140 peer-reviewed publications and she has provided lectures at several national and international meetings including SIE, SIES, EHA and ASH. Current Scopus H-index is 42, total IF is 1559.7 with 6560 citations.